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Safe and effective vaccines are now available for protection against hepatitis B, a serious liver infection that can result in cirrhosis and liver cancer.

The Centers for Disease Control and the American Academy of Pediatrics recommend that all newborns, infants and children, especially sexually active teenagers be vaccinated against hepatitis B.

Vaccination is also recommended for individuals at high risk of being infected with the hepatitis B virus (HBV). These include:

  • Health care workers, including doctors, dentists, nurses, blood and lab technicians;
  • Emergency workers - including paramedics, fire fighters and police;
  • Hemodialysis patients;
  • Military personnel;
  • Morticians and embalmers;
  • Patients and staff of institutions for the mentally handicapped, inmates of long-term correctional institutions;
  • Ethnic groups with a high rate of hepatitis B including Chinese, Koreans, Indochinese, Filipinos, Alaskan Eskimos, Haitians, and American Indians;
  • People with multiple sexual partners;
  • Intravenous drug users;
  • Recipients of certain blood products;
  • Household contacts and sex partners of hepatitis B carriers;
  • International travelers


Those who are already infected will not benefit from vaccination. However, infants born of mothers who are carriers of the hepatitis B virus can be protected. A simple blood test can determine whether someone is a hepatitis B carrier.


Immunization requires three doses of vaccine according to the following schedule:

  • 1st dose: For infants born to infected mothers - within 12 hours.
    For infants born to mothers who test negative - within one to
    two months following delivery.
  • 2nd dose: 1 month later.
  • 3rd dose: 6 months after the first dose.

Administration is by intramuscular injection in the thigh or upper arm.

Hepatitis B is caused by a virus and is spread through blood, other body fluids and contaminated needles.

In the United States, there are about 1,000,000 carriers, who have no symptoms but can pass the infection on to others, and an estimated 300,000 new cases a year.

A significant number of people with hepatitis B have no symptoms. Others may have flu-like symptoms: fever, fatigue, muscle or joint pain, appetite loss, nausea and vomiting. Twenty-five to thirty-five percent have symptoms such as jaundice, a yellowing of the skin and eyes, that indicates liver damage.

Five to ten percent of hepatitis B young adult victims become chronic carriers, often without knowing it. Nine of ten infants infected become chronic carriers. They are at increased risk of developing cirrhosis and liver cancer.

The vaccines provide immunization in about 90 percent of recipients.

TEST RESULTS AND INDICATIONS FOR VACCINATION

Checking To See If The Patient Needs Hepatitis B Vaccine: One must use a combination of two tests to truly determine if a patient is a carrier, already immune or still susceptible to the hepatitis B virus. The physician can use HBsAg and Anti-HBc or HBsAg and Anti-HBs.

HBsAg
Anti-HBc

Positive
Positive

The patient is a carrier.

DOES NOT NEED THE HEPATITIS B VACCINE.
HBsAg
Anti-HBc

Negative
Positive

The patient has been exposed and has probably developed natural immunity. Alternatively, he may be an individual with an isolated Anti-HBc result (HBsAg negative, Anti-HBc positive and Anti-HBs negative)

DOES NOT NEED THE VACCINE.
HBsAg
Anti-HBc

Negative
Negative

The patient is susceptible to hepatitis B.

GIVE THE FULL VACCINE PROTOCOL.
HBsAg
Anti-HBc

Positive
Negative

The patient is infected with hepatitis B and is probably a carrier.

DOES NOT NEED THE HEPATITIS B VACCINE.
HBsAg
Anti-HBc
Negative
Positive
The patient has already been exposed and has developed natural immunity or has been successfully vaccinated. DOES NOT NEED THE VACCINE.
HBsAg
Anti-HBc

Negative
Negative

The patient is susceptible.

SHOULD RECEIVE THE VACCINE.


The American Liver Foundation is the only national voluntary health organization dedicated to preventing, treating, and curing hepatitis and all other liver and gallbladder diseases through research and education.


American Liver Foundation
1425 Pompton Avenue, Cedar Grove, NJ 07009
1-800-223-0179

Copyright © 1995
The American Liver Foundation